Services

We are committed to advancing research through our comprehensive suite of service capabilities, ensuring high-quality results and innovative solutions backed by scientific evidence from our own laboratory and research.

State of the art PC2 facility

Bionyeri is equipped with cutting-edge laboratory facilities, including an OGTR accredited PC2 laboratory. This advanced infrastructure ensures stringent safety standards and regulatory compliance, enabling sophisticated and secure research operations.

Disease models – neurodegenerative and cancer

Bionyeri can conduct in vitro experiments with large collection of human cell lines including:

  • Brain (Glioma – Astrocytoma, Glioblastoma multiforme, Neuroblastoma)
  • Breast (hormone-positive, triple-negative, HER2 overexpressed)
  • Colorectal
  • Liver
  • Ovarian

Analytical services

Drug testing and screening
  • Study in vitro – absorption, distribution, metabolism, and excretion–toxicity (ADMET) in pharmacokinetics.

High-throughput screening
  • Rapid testing of multiple compounds for ADMET properties using automated systems
Blood-brain barrier permeability studies
  • Transwell assay to study drug permeability
Blood and urine biomarker studies for clinical trials
  • Inflammatory markers
  • Cancer markers
  • Immune markers
  • Neurological diseases related markers

Flow cytometry

  • Cytokine/Chemokine measurement: Concomitant analysis of 13 cytokines
  • Intracellular calcium assay
  • Cell cycle analysis

Microplate reader assays

  • Antioxidant: ORAC
  • Cell proliferation
  • Kynurenine pathway metabolites
  • Nitric oxide
  • COX 1 and 2
  • Various enzyme activity
  • Drug toxicity
  • Reactive Oxygen Species (ROS)
  • Apoptosis
  • Amyloid beta
  • Tau phosphorylation
  • Synuclein

Chromatography

  • Advanced analytical techniques: High-resolution Orbitrap LC-MS, Triple quadrupole Gas chromatography-mass spectrometry (GC-MS), High-performance liquid Chromatography (HPLC), and GC-FID
  • Drug characterisation and metabolomics

Artificial Intelligence

  • Accelerated optimisation of drugs or natural product formulations
  • AI-powered predictive models for drug development